STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
areBIclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa)    
Predicted Functional Partners:
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.842
leuD
3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.818
ANW20366.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.738
ANW17877.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.702
ANW17876.1
DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
       0.649
ANW17689.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.548
kipI
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.539
ANW20980.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.536
ccaR
Positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.529
ANW20799.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.523
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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