STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANW17933.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)    
Predicted Functional Partners:
ANW21649.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.746
ANW21833.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
    0.642
ANW17935.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.641
ilvB1
Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.528
ANW21832.1
Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.514
ANW17347.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.501
ANW17934.1
Glucose sorbosone dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.472
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.415
ANW19729.1
Acetoin utilization protein AcuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  0.408
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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