STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cefDPenicillin epimerase; Catalyzes the reversible isomerization between isopenicillin N and penicillin N; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (398 aa)    
Predicted Functional Partners:
cefE
Cephalosporin hydroxylase; Catalyzes the step from penicillin N to deacetoxy- cephalosporin C.
    
 0.983
ANW20771.1
SUF system NifU family Fe-S cluster assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.969
pcbC
Penicillin synthase; Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin.
     
 0.944
ANW20436.1
Peptidase C45; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.913
ANW20769.1
Fe-S cluster assembly ATPase SufC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.911
sufB
Fe-S cluster assembly protein SufB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.890
ANW20767.1
Fe-S cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.868
ANW20564.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.735
pcd
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
       0.599
ANW16726.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.577
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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