STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cmcH3-hydroxymethylcephem carbamoyltransferase; Catalyzes the carbamoylation reaction in the cephamycin biosynthesis; Belongs to the NodU/CmcH family. (521 aa)    
Predicted Functional Partners:
cefF
Cephalosporin hydroxylase; Hydroxylation of desacetoxicephalosporin C in 3'position to form deacetylcephalosporin C.
    
 0.967
ANW16839.1
Acetylxylan esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
cmcI
Cephalosporin hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.788
ANW17658.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
  
 0.625
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.613
ANW17657.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.612
cmcJ
7-alpha-cephem-methoxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.589
pcbAB
Non-ribosomal peptide synthetase; Each of the constituent amino acids of ACV are activated as aminoacyl-adenylates with peptide bonds formed through the participation of amino acid thioester intermediates; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.525
ANW17186.1
Non-ribosomal peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.432
ANW16808.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.409
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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