STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORF12MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)    
Predicted Functional Partners:
ANW17893.1
Calcium-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.616
ANW19629.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.601
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.592
ANW21880.1
LmbE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.587
ANW19366.1
Chloride channel core; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.544
ccaR
Positive regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.505
ceaS
Decarboxylase; Involved in the biosynthesis of the beta-lactamase inhibitor, clavulanic acid. Catalyzes the thiamine diphosphate (ThDP) dependent condensation of D-glyceraldehyde-3-phosphate (D-G3P) with L-arginine to yield the beta-amino acid, N2-(2-carboxyethyl)arginine (CEA) via a beta-elimination resulting in the formation of an enol which undergoes a second elimination to generate the alpha,beta-unsaturated acryloyl- ThDP; Belongs to the TPP enzyme family.
      
 0.469
ANW21654.1
1,4-dihydroxy-2-naphtoate octaprenyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.469
ANW20482.1
Twin-arginine translocation pathway signal; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.466
bls
Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparagine synthetase family.
      
 0.465
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.