STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cs2Clavaminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)    
Predicted Functional Partners:
pah
Agmatinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family.
 
 
 0.904
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.781
ANW17657.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.688
ANW17658.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.688
ceaS
Decarboxylase; Involved in the biosynthesis of the beta-lactamase inhibitor, clavulanic acid. Catalyzes the thiamine diphosphate (ThDP) dependent condensation of D-glyceraldehyde-3-phosphate (D-G3P) with L-arginine to yield the beta-amino acid, N2-(2-carboxyethyl)arginine (CEA) via a beta-elimination resulting in the formation of an enol which undergoes a second elimination to generate the alpha,beta-unsaturated acryloyl- ThDP; Belongs to the TPP enzyme family.
 
  
 0.635
ANW18148.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.591
gcas
Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.570
ANW17186.1
Non-ribosomal peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.557
cs1
Clavaminate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.505
bls
Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the asparagine synthetase family.
  
  
 0.501
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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