STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW18186.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)    
Predicted Functional Partners:
parE
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.912
gyrBS
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.912
ANW17151.1
Recombinase RmuC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.890
ANW21740.1
GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANW16837.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANW17210.1
Multi-component regulatory system-3; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
ANW17885.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
ANW17888.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
ANW21846.1
Multi-component regulatory system-8; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
ANW18850.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.508
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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