STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW18234.1Mycothiol system anti-sigma-R factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)    
Predicted Functional Partners:
ANW18235.1
RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily.
  
 
 0.992
ANW18232.1
Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.788
ANW18233.1
Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.735
ANW18236.1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.725
ANW18237.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SOS response-associated peptidase family.
       0.704
ANW21852.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.663
ANW21853.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.658
bldC
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.644
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
       0.624
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
       0.619
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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