STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW18318.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)    
Predicted Functional Partners:
mshB
N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway.
  
    0.742
ANW18316.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
ANW19145.1
N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.736
ANW18319.1
Peptidase S9; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.520
ANW21694.1
Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.478
ANW21692.1
Phage baseplate protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.472
ccsA
Cytochrome C biogenesis protein ResC; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.454
ANW19078.1
Thiol-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.454
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.428
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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