STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANW18520.1Phosphoribose diphosphate--decaprenyl-phosphate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. (325 aa)    
Predicted Functional Partners:
ANW18521.1
Phosphatidic acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.957
ANW18522.1
decaprenylphosphoryl-beta-D-ribose oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.951
ANW18523.1
decaprenylphospho-beta-D-erythro-pentofuranosid- 2-ulose 2-reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.920
ANW18519.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.711
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.685
chlI
Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.644
mltG
Hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family.
   
    0.579
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.571
parC
DNA topoisomerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.497
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.497
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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