STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW18807.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)    
Predicted Functional Partners:
kynU
Hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
  
  
 0.916
ANW18806.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.827
ANW18805.1
acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.820
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
  
 0.777
adhA
Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.632
cmcJ
7-alpha-cephem-methoxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.468
ANW21537.1
IclR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.445
ANW22092.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.420
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
Server load: low (24%) [HD]