STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW19025.1Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 0.882
ANW19026.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.832
ANW19027.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.772
ANW19023.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.677
ANW19022.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.615
ANW21994.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.609
ANW17758.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.592
sya
alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 
  0.582
ANW20808.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.575
moaD
Molybdopterin synthase sulfur carrier subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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