STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANW19252.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0232 family. (211 aa)    
Predicted Functional Partners:
recF
DNA replication/repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family.
  
  
 0.901
ANW19249.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.899
ANW19254.1
6-phosphogluconate dehydrogenase (decarboxylating); Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.870
dpoB
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
   
 0.850
ANW22017.1
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.804
ANW19801.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
ANW21203.1
MerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.703
ANW19977.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.702
ANW20519.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.689
wblE
WhiB family transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
  
     0.664
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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