Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ANW19589.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)    
Predicted Functional Partners:
ANW19591.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.875
ANW19590.1
DNA mismatch repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.873
ANW19588.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.553
guaB2
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 0.552
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.539
ANW18042.1
Cellulose-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.518
ANW20472.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.493
ANW21608.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.493
ANW20675.1
Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.455
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.448
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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