STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW19598.1DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (249 aa)    
Predicted Functional Partners:
ANW19145.1
N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.645
ANW17758.1
Hybrid sensor histidine kinase/response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.626
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.623
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.623
ANW19615.1
DUF4913 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANW19616.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANW19617.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.545
ANW19629.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.464
ANW20032.1
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.440
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.