STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW20140.1Nucleoside diphosphate pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)    
Predicted Functional Partners:
nnrE
NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of b [...]
  
 0.926
ANW20139.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
rnr
Ribonuclease II; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.724
rnpH
Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
    
 0.669
ANW18283.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.619
ANW19072.1
RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.619
ANW21403.1
DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.619
ANW20141.1
SAICAR synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.474
ANW20142.1
Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.464
ANW20138.1
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.452
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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