STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANW20839.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)    
Predicted Functional Partners:
ANW20838.1
C-5 sterol desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.870
ANW20837.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.708
ANW22064.1
DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.669
ANW20836.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.618
ANW20835.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.593
ANW20833.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.550
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.506
ANW17499.1
Cell division protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.486
hmuO
Heme oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.412
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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