STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANW20877.116S/23S rRNA (cytidine-2'-O)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)    
Predicted Functional Partners:
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.974
ANW20876.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.879
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.786
ANW20875.1
Sterol-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.772
ANW20274.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.712
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.702
ANW19257.1
Membrane protein insertion efficiency factor YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
      
 0.699
whiB
DNA-binding protein; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
      
 0.664
gidB
16S rRNA (guanine(527)-N(7))-methyltransferase; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
   
 0.649
ANW20006.1
Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.641
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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