STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (513 aa)    
Predicted Functional Partners:
glpD1
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.986
ANW18568.1
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.958
glpF2
Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 
 0.915
ANW18453.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
ANW22067.1
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.906
glpK-2
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 
0.901
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
 0.868
ANW21994.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.857
glpF1
Glycerol transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MIP/aquaporin (TC 1.A.8) family.
 
 
 0.847
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.758
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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