STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANW22092.1Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)    
Predicted Functional Partners:
ANW21221.1
Pyridoxamine 5-phosphate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.821
ANW18811.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.626
ANW18856.1
Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.617
ANW18769.1
Luciferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.594
nnrE
NAD(P)H-hydrate dehydratase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of b [...]
  
    0.551
ANW21255.1
3-ketoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  0.532
gpdA
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
   0.501
ANW17142.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.498
ANW17657.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.494
ANW17658.1
Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.494
Your Current Organism:
Streptomyces clavuligerus
NCBI taxonomy Id: 1901
Other names: ATCC 27064, BCRC 11518, CBS 226.75, CCRC 11518, CCRC:11518, CECT 3125, DSM 40751, DSM 738, IFO 13307, IMET 43657, JCM 4710, KCTC 9095, NBRC 13307, NCIMB 12785, NCIMB 14335, NRRL 3585, S. clavuligerus, Streptomyces clavuligerus ATCC 27064, Streptomyces clavuligerus NRRL 3585, VKM Ac-602
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