MK0148 protein (Methanopyrus kandleri) - STRING interaction network

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second shell of interactors

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Predicted Interactions

gene neighborhood

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Score

MK0148

GTPase - translation elongation factor. (459 aa)

Predicted Functional Partners:

rpsE

0.980

rpsC

0.979

rps6A

0.977

sui2

0.976

rpsL

0.972

rpsB

0.972

rpsG

0.971

rps4A

0.970

rps1A

0.970

rplB

0.969

Your Current Organism:

Methanopyrus kandleri

NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MK0148	rplB	MK0148	MK0412	GTPase - translation elongation factor.	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	0.969
MK0148	rps1A	MK0148	MK1461	GTPase - translation elongation factor.	Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.	0.970
MK0148	rps4A	MK0148	MK1220	GTPase - translation elongation factor.	Ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.	0.970
MK0148	rps6A	MK0148	MK1446	GTPase - translation elongation factor.	Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family.	0.977
MK0148	rpsB	MK0148	MK1578	GTPase - translation elongation factor.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.972
MK0148	rpsC	MK0148	MK0842	GTPase - translation elongation factor.	Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.	0.979
MK0148	rpsE	MK0148	MK0029	GTPase - translation elongation factor.	Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.	0.980
MK0148	rpsG	MK0148	MK0680	GTPase - translation elongation factor.	Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.971
MK0148	rpsL	MK0148	MK0681	GTPase - translation elongation factor.	Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.972
MK0148	sui2	MK0148	MK0419	GTPase - translation elongation factor.	Translation initiation factor eIF2-alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.	0.976
rplB	MK0148	MK0412	MK0148	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	GTPase - translation elongation factor.	0.969
rplB	rps1A	MK0412	MK1461	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S3AE; Belongs to the eukaryotic ribosomal protein eS1 family.	0.999
rplB	rps4A	MK0412	MK1220	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S4E; Belongs to the eukaryotic ribosomal protein eS4 family.	0.999
rplB	rps6A	MK0412	MK1446	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family.	0.999
rplB	rpsB	MK0412	MK1578	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.999
rplB	rpsC	MK0412	MK0842	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.	0.999
rplB	rpsE	MK0412	MK0029	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.	0.999
rplB	rpsG	MK0412	MK0680	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.	0.999
rplB	rpsL	MK0412	MK0681	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family.	0.999
rplB	sui2	MK0412	MK0419	Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.	Translation initiation factor eIF2-alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.	0.795