STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEDephospho-CoA kinase; Belongs to the UPF0200 family. (196 aa)    
Predicted Functional Partners:
MK0399
Uncharacterized protein conserved in archaea; Belongs to the UPF0201 family.
 
    0.885
MK0398
Predicted RNA-binding protein containing the S4 domain.
       0.800
sen2_2
tRNA splicing endonuclease; Belongs to the tRNA-intron endonuclease family. Archaeal short subfamily.
       0.773
truB
Pseudouridine synthase of the TruB family; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
 
  
 0.729
dfp
Phosphopantothenoylcysteine synthetase/decarboxylase.
 
 
 0.717
pppA
Prepilin-cleaving (type IV) signal peptidase.
  
  
 0.697
nadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.648
infB_2
Translation initiation factor 2, GTPase; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
     
 0.645
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
    0.636
MK0396
SAM-dependent methyltransferase.
   
 
 0.636
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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