STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hycBFe-S-cluster-containing hydrogenase component. (167 aa)    
Predicted Functional Partners:
ehaO
Ni,Fe-hydrogenase III large subunit.
  
 
 0.890
ehaN
Ni,Fe-hydrogenase III small subunit.
  
 
 0.889
cooC_2
CO dehydrogenase maturation factor.
  
  
 0.853
porB_2
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
  
 0.836
porA_2
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
  
 0.831
porG_2
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
  
  
 0.821
MK0727
Ferredoxin.
     
 0.820
MK0734
Predicted RNA-binding protein.
  
    0.815
ehaJ
Membrane protein related to formate hydrogenlyase subunit 4.
  
 
 0.807
sucC
Succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
       0.773
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.