node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MK1164 | MK1165 | MK1164 | MK1165 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Uncharacterized protein. | 0.401 |
MK1164 | MK1436 | MK1164 | MK1436 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Topoisomerase V. | 0.616 |
MK1164 | elp3 | MK1164 | MK1052 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetylase domain. | 0.754 |
MK1164 | nop1 | MK1164 | MK0560 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | 0.619 |
MK1164 | ssh10b_1 | MK1164 | MK0715 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.790 |
MK1164 | ssh10b_2 | MK1164 | MK1089 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.790 |
MK1164 | top6B | MK1164 | MK0921 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.542 |
MK1164 | topA | MK1164 | MK1604 | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | Topoisomerase IA. | 0.733 |
MK1165 | MK1164 | MK1165 | MK1164 | Uncharacterized protein. | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | 0.401 |
MK1436 | MK1164 | MK1436 | MK1164 | Topoisomerase V. | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | 0.616 |
MK1436 | ssh10b_1 | MK1436 | MK0715 | Topoisomerase V. | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.526 |
MK1436 | ssh10b_2 | MK1436 | MK1089 | Topoisomerase V. | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | 0.526 |
MK1436 | top6B | MK1436 | MK0921 | Topoisomerase V. | DNA topoisomerase VI, subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.526 |
MK1436 | topA | MK1436 | MK1604 | Topoisomerase V. | Topoisomerase IA. | 0.879 |
elp3 | MK1164 | MK1052 | MK1164 | ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetylase domain. | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | 0.754 |
elp3 | topA | MK1052 | MK1604 | ELP3 component of the RNA polymerase II complex, consists of an N-terminal BioB/LipA-like domain and a C-terminal histone acetylase domain. | Topoisomerase IA. | 0.439 |
nop1 | MK1164 | MK0560 | MK1164 | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | 0.619 |
nop1 | topA | MK0560 | MK1604 | Fibrillarin-like rRNA methylase; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. | Topoisomerase IA. | 0.430 |
ssh10b_1 | MK1164 | MK0715 | MK1164 | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Predicted nuclease of the micrococcal nuclease (thermonuclease) family. | 0.790 |
ssh10b_1 | MK1436 | MK0715 | MK1436 | Archaea-specific DNA-binding protein; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes (By similarity); Belongs to the histone-like Alba family. | Topoisomerase V. | 0.526 |