STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiX3-polyprenyl-4-hydroxybenzoate decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (184 aa)    
Predicted Functional Partners:
ubiD
Predicted decarboxylase related 3-polyprenyl-4-hydroxybenzoate decarboxylase.
  
 0.963
arsA
Arsenite transporting ATPase.
     
 0.900
ubiA
4-hydroxybenzoate polyprenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
     
 0.710
cooS
Carbon monoxide dehydrogenase catalytic subunit; CODH oxidizes carbon monoxide coupled, via CooF, to the reduction of a hydrogen cation by a hydrogenase (possibly CooH).
      
 0.622
MK1466
Uncharacterized membrane protein.
       0.576
ispA
Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
     
 0.484
mfnA
Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
  
    0.466
MK1542
Predicted Zn-dependent hydrolase of the beta-lactamase superfamily; Belongs to the UPF0173 family.
   
   0.443
suhB
Myo-inositol-1(or 4)-monophosphatase; Archaea-specific fructose-1,6-bisphosphatase fused to predicted pyrophosphatase of the PRA-PH family.
       0.420
MK0194
HD superfamily phosphohydrolase.
  
    0.414
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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