STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaDPredicted nucleotidyltransferase of the HIGH superfamily; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the eukaryotic CoaD family. (157 aa)    
Predicted Functional Partners:
MK1453
Uncharacterized protein conserved in archaea; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).
 
  
 0.988
MK1503
Uncharacterized conserved protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
      0.982
dfp
Phosphopantothenoylcysteine synthetase/decarboxylase.
    
 0.920
MK1505
Predicted ATPase of the PP-loop superfamily.
       0.773
hyaD_1
Ni,Fe-hydrogenase maturation factor.
       0.636
mfnA
Pyridoxal-phosphate-dependent enzyme related to glutamate decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
       0.636
MK1501
Predicted transcriptional regulator containing a DNA-binding HTH domain.
       0.636
MK1502
Predicted transcriptional regulator containing the CopG/Arc/MetJ DNA-binding domain and a 3H domain; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family.
       0.636
MK1560
Predicted permease.
  
  
 0.536
MK1506
Uncharacterized conserved protein.
       0.512
Your Current Organism:
Methanopyrus kandleri
NCBI taxonomy Id: 190192
Other names: M. kandleri AV19, Methanopyrus kandleri AV19, Methanopyrus kandleri str. AV19
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