node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FN0544 | FN0597 | FN0544 | FN0597 | ADP-heptose:LPS heptosyltransferase II. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.489 |
FN0544 | FN1240 | FN0544 | FN1240 | ADP-heptose:LPS heptosyltransferase II. | Lipopolysaccharide core biosynthesis protein rfaY. | 0.901 |
FN0544 | lpxC | FN0544 | FN0593 | ADP-heptose:LPS heptosyltransferase II. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.407 |
FN0544 | lpxD | FN0544 | FN1909 | ADP-heptose:LPS heptosyltransferase II. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.462 |
FN0544 | trmB | FN0544 | FN1606 | ADP-heptose:LPS heptosyltransferase II. | 3-deoxy-D-manno-octulosonic-acid transferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; In the C-terminal section; belongs to the class I-like SAM- binding methyltransferase superfamily. TrmB family. | 0.935 |
FN0597 | FN0544 | FN0597 | FN0544 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | ADP-heptose:LPS heptosyltransferase II. | 0.489 |
FN0597 | FN0903 | FN0597 | FN0903 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.800 |
FN0597 | FN1016 | FN0597 | FN1016 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Lipid A biosynthesis lauroyl acyltransferase. | 0.728 |
FN0597 | kdsB | FN0597 | FN0807 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.824 |
FN0597 | lpxA | FN0597 | FN0595 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.990 |
FN0597 | lpxC | FN0597 | FN0593 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.945 |
FN0597 | lpxD | FN0597 | FN1909 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.986 |
FN0597 | lpxK | FN0597 | FN1130 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.984 |
FN0597 | trmB | FN0597 | FN1606 | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 3-deoxy-D-manno-octulosonic-acid transferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; In the C-terminal section; belongs to the class I-like SAM- binding methyltransferase superfamily. TrmB family. | 0.835 |
FN0903 | FN0597 | FN0903 | FN0597 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.800 |
FN0903 | FN1016 | FN0903 | FN1016 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | Lipid A biosynthesis lauroyl acyltransferase. | 0.638 |
FN0903 | kdsB | FN0903 | FN0807 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.886 |
FN0903 | lpxA | FN0903 | FN0595 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | Acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.817 |
FN0903 | lpxC | FN0903 | FN0593 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | 0.827 |
FN0903 | lpxD | FN0903 | FN1909 | Polysialic acid capsule expression protein kpsF; Belongs to the SIS family. GutQ/KpsF subfamily. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.817 |