STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN85_0505Delta-aminolevulinic acid dehydratase Hemb; arCOG04300; gene: hemB; Belongs to the ALAD family. (322 aa)    
Predicted Functional Partners:
BTN85_1632
Porphobilinogen deaminase HemC; arCOG04299; gene: hemC.
 
 0.993
BTN85_1857
Uroporphyrinogen-III synthase HemD; arCOG02048; gene: hemD.
 
 0.986
hemL
Glutamate-1-semialdehyde aminotransferase HemL; arCOG00918; gene: hemL.
 
 
 0.982
BTN85_1631
Uroporphyrinogen-III methylase; arCOG00644; gene: cysG.
  
 
 0.885
BTN85_1460
L-tyrosine decarboxylase, PLP-dependent protein MfnA; arCOG00027; gene: mfnA.
    
 0.880
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.849
BTN85_1855
Siroheme synthase CysG; arCOG01044; gene: cysG.
    
 0.834
BTN85_0167
Ornithine/acetylornithine aminotransferase argD; arCOG00914; gene: argD; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.804
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
     
 0.615
cysS
Cysteinyl-tRNA synthetase; arCOG00486; gene: cysS.
     
 0.565
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
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