STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN85_0641CBS domain containing protein; arCOG00600. (126 aa)    
Predicted Functional Partners:
BTN85_0640
Phosphatidylglycerophosphate synthase PgsA; arCOG00670; gene: pgsA; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
     
 0.647
guaAB
GMP synthase PP-ATPase domain/subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.574
guaAA
GMP synthase - Glutamine amidotransferase domain; Catalyzes the synthesis of GMP from XMP.
  
 
 0.551
BTN85_1965
AICAR transformylase/IMP cyclohydrolase PurH; arCOG02824; gene: purH.
  
 
 0.534
BTN85_0318
Rhodanese Homology Domain fused to beta-lactamase superfamily hydrolase; arCOG00517.
  
 
   0.526
BTN85_0758
Pyruvate/2-oxoglutarate dehydrogenase complex (E3) component Lpd; arCOG01068; gene: lpd; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
   0.500
BTN85_1107
ATPase involved in replication control Cdc46/Mcm family; arCOG00439; gene: mCM2; Belongs to the MCM family.
       0.497
BTN85_0638
Putative glutamine amidotransferase involved in pyridoxine biosynthesis; arCOG00034; gene: PDX2.
    
  0.487
pdxS
Pyridoxine biosynthesis enzyme SNZ1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.486
BTN85_1691
5'-deoxynucleotidase HD superfamily hydrolase; arCOG04311.
  
  
  0.475
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
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