STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN85_0916Methyl coenzyme M reductase gamma subunit McrG; arCOG04858; gene: mcrG. (257 aa)    
Predicted Functional Partners:
BTN85_0914
Methyl coenzyme M reductase beta subunit McrB; arCOG04860; gene: mcrB.
  
 0.999
BTN85_0917
Methyl coenzyme M reductase alpha subunit McrA; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
  
 0.999
BTN85_0915
Methyl coenzyme M reductase subunit D McrD; arCOG04859; gene: mcrD.
  
 
 0.990
BTN85_0921
Methyl coenzyme M reductase subunit C McrC; arCOG03225; gene: mcrC.
  
 
 0.974
BTN85_0890
Methanol-cobalamin methyltransferase B subunit MtaB; arCOG03330; gene: mtaB.
     
 0.753
BTN85_0888
Methanogenic corrinoid protein MtaC; arCOG02032; gene: mtaC.
     
 0.752
BTN85_1646
arCOG03325; gene: mtbA.
     
 0.748
BTN85_0922
CoB--CoM heterodisulfide reductase subunit E; arCOG05014; gene: hdrE.
     
 0.747
BTN85_0869
arCOG03325; gene: mtbA.
     
 0.746
BTN85_0493
Coenzyme F420-reducing hydrogenase, gamma subunit; arCOG02472; gene: frhG.
   
 
 0.740
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
Server load: low (20%) [HD]