STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN85_1675Dihydropteroate synthase FolP; arCOG01978; gene: folP. (492 aa)    
Predicted Functional Partners:
BTN85_1907
Anthranilate/para-aminobenzoate synthase component I TrpE; arCOG02014; gene: trpE.
  
 
 0.927
ilvE
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.908
glyA
Glycine/serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.903
mptE
78-Dihydro-6-hydroxymethylpterin- pyrophosphokinase HPPK Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
 
  
 0.854
BTN85_1986
Cysteine synthase CysK; arCOG01430; gene: cysK.
    
 0.853
mptD
Dihydroneopterin aldolase, FolB; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD).
    
 0.836
thrB
Homoserine kinase ThrB; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
    
 0.825
BTN85_0446
Homoserine dehydrogenase ThrA; arCOG01351; gene: thrA.
    
 0.824
BTN85_0319
Putative sugar kinase; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
 
  
  0.823
BTN85_1665
F(420)-0:gamma-glutamyl ligase F420 coenzyme biosynthesis enzyme CofE; arCOG02714; gene: cofE.
    
 0.821
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
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