STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rps12Ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)    
Predicted Functional Partners:
rpl11
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
 
 0.999
rpl1
Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
  
 
 0.999
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
 
 0.999
rps17e
Ribosomal protein S17E; arCOG01885; gene: RPS17A; Belongs to the eukaryotic ribosomal protein eS17 family.
   
 0.999
BTN85_0336
Endonuclease Nob1 consisting of PIN domain and Zn-ribbon module; arCOG00721; gene: nob1.
  
 
  0.999
BTN85_0377
Translation initiation factor 1 (eIF-1/SUI1); arCOG04223; gene: SUI1; Belongs to the SUI1 family.
   
 
 0.999
eif1a
Translation initiation factor 1 (IF-1); Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
 0.999
eif5a
Translation elongation factor P (EF-P)/(eIF-5A); Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 0.999
rps24e
Ribosomal protein S24E; arCOG04182; gene: RPS24A; Belongs to the eukaryotic ribosomal protein eS24 family.
   
 0.999
rps15
Ribosomal protein S15P; arCOG04185; gene: rpsO.
  
 0.999
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.