STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN85_2206ATPase involved in replication control Cdc46/Mcm family; arCOG00439; gene: mCM2. (909 aa)    
Predicted Functional Partners:
BTN85_1107
ATPase involved in replication control Cdc46/Mcm family; arCOG00439; gene: mCM2; Belongs to the MCM family.
  
  
  0.926
BTN85_0693
DNA polymerase PolB3; arCOG00328; gene: polB3.
  
 0.854
BTN85_1830
DNA polymerase PolB2 inactivated; arCOG00329; gene: polB2.
  
 0.849
BTN85_0153
Cdc6-related protein AAA superfamily ATPase; Involved in regulation of DNA replication.
   
 0.805
BTN85_1845
Cdc6-related protein AAA superfamily ATPase; arCOG00467; gene: CDC6.
   
 0.805
BTN85_1846
Cdc6-related protein AAA superfamily ATPase; Involved in regulation of DNA replication.
   
 0.805
BTN85_1860
Cdc6-related protein AAA superfamily ATPase; Involved in regulation of DNA replication.
   
 0.805
priL
Eukaryotic-type DNA primase large subunit PRI2; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
   
 
 0.803
priS
Eukaryotic-type DNA primase catalytic small subunit PRI1; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer ext [...]
   
 0.768
BTN85_2205
Hypothetical protein.
       0.762
Your Current Organism:
Methanohalarchaeum thermophilum
NCBI taxonomy Id: 1903181
Other names: C. Methanohalarchaeum thermophilum, Candidatus Methanohalarchaeum thermophilum, Euryarchaeota archaeon HMET1, archaeon HMET1, strain HMET1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.