Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pahPhenylalanine hydroxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (296 aa)    
Predicted Functional Partners:
phhb
Pterin-4-alpha-carbinolamine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.997
tyrB
Aromatic-amino-acid aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.959
XCC0436
4-hydroxyphenylpyruvate dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.954
pheA-2
P-protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.932
hisC
Aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.921
hisC-2
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.921
hisC-3
Histidinol-phosphate aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.921
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.911
folA
Dihydrofolate reductase type III; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
 0.906
ptr1
Pteridine reductase 1; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
  0.901
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
Server load: low (12%) [HD]