Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fabH3-oxoacyl-[ACP] synthase III; Involved in olefin biosynthesis. Catalyzes a non- decarboxylative head-to-head Claisen condensation of two acyl-CoA molecules, generating an (R)-2-alkyl-3-oxoalkanoate. Is active with fatty acyl-CoA substrates that ranged from C(8) to C(16) in length, and is the most active with palmitoyl-CoA and myristoyl-CoA. Belongs to the thiolase-like superfamily. OleA family. (338 aa)    
Predicted Functional Partners:
dhaA
Haloalkane dehalogenase; Involved in olefin biosynthesis. Catalyzes the elimination of carbon dioxide from beta-lactones to form the final olefin product. Belongs to the AB hydrolase superfamily.
 
   
 0.972
fabD
Malonyl CoA-ACP transacylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.958
fabB
beta-ketoacyl-[ACP] synthase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.941
oleC
AMP-ligase; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl- 3-hydroxyalkanoic acids to beta-lactones in the presence of ATP ; Belongs to the ATP-dependent AMP-binding enzyme family.
 
   
 0.938
fabF
3-oxoacyl-[ACP] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.933
cdh
NAD(P)H steroid dehydrogenase; Involved in olefin biosynthesis. Catalyzes the reversible stereospecific NADPH- dependent reduction of 2-alkyl-3-oxoalkanoic acids to 2-alkyl-3- hydroxyalkanoic acids (By similarity); Belongs to the 3-beta-HSD family.
 
   
 0.917
fabF-2
beta-ketoacyl-[ACP] synthase II; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.916
fabZ
(3r)-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
  
 0.907
fabA
beta-hydroxydecanoyl-ACP dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.
  
  
 0.818
mdcH
Malonyl CoA-ACP transacylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.806
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
Server load: low (12%) [HD]