| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC0225 | XCC3165 | XCC0225 | XCC3165 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.631 |
| XCC0225 | rplC | XCC0225 | XCC0895 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.668 |
| XCC0225 | rplN | XCC0225 | XCC0905 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.663 |
| XCC0225 | rplO | XCC0225 | XCC0914 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.666 |
| XCC0225 | rplQ | XCC0225 | XCC0920 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L17; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.680 |
| XCC0225 | rplU | XCC0225 | XCC1149 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.663 |
| XCC0225 | rsfS | XCC0225 | XCC2615 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.636 |
| XCC0225 | thdF | XCC0225 | XCC4238 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.621 |
| XCC0225 | truD | XCC0225 | XCC1704 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Hydrogenase subunit; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.636 |
| XCC0225 | yhbZ | XCC0225 | XCC1151 | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.667 |
| XCC3165 | XCC0225 | XCC3165 | XCC0225 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridylate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.631 |
| XCC3165 | rplC | XCC3165 | XCC0895 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.692 |
| XCC3165 | rplN | XCC3165 | XCC0905 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.620 |
| XCC3165 | rplO | XCC3165 | XCC0914 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.794 |
| XCC3165 | rplQ | XCC3165 | XCC0920 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L17; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.740 |
| XCC3165 | rplU | XCC3165 | XCC1149 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.741 |
| XCC3165 | rsfS | XCC3165 | XCC2615 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.766 |
| XCC3165 | thdF | XCC3165 | XCC4238 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Thiophene and furan oxidation protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.752 |
| XCC3165 | truD | XCC3165 | XCC1704 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Hydrogenase subunit; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.684 |
| XCC3165 | yhbZ | XCC3165 | XCC1151 | tRNA/rRNA methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.584 |