STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (298 aa)    
Predicted Functional Partners:
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.988
XCC1210
Tryptophan 2,3-dioxygenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the tryptophan 2,3-dioxygenase family.
  
  
 
0.928
tpmT
Thiopurine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
      
 0.812
glbN
Cyanoglobin; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.812
XCC1068
Possible DNA methylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
      
 0.810
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.806
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
  0.800
XCC0056
Hemolysin III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
      
 0.784
hly3
Hemolysin III; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
      
 0.784
tspO
Tryptophan-rich sensory protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
      
 0.780
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.