Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ptps6-pyruvoyl tetrahydrobiopterin synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (117 aa)    
Predicted Functional Partners:
queE
Radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
 
 
 0.996
folE
GTP cyclohydrolase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.978
exsB
Transcriptional regulator; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
  
 0.975
folE2
Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.939
phoA
Alkaline phosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the alkaline phosphatase family.
     
  0.900
XCC4042
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
  0.900
queF
Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
  
  
 0.889
hisI
phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase bifunctional enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the PRA-PH family.
     
 0.691
queA
S-adenosylmethionine: tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
     
 0.559
XCC0588
Conserved hypothetical protein; Putative; ORF located using Glimmer/Genemark.
       0.545
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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