node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddlB-2 | ftsI | XCC0727 | XCC0720 | D-alanine-D-alanine ligase B; Cell wall formation. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | 0.942 |
ddlB-2 | ftsL | XCC0727 | XCC0719 | D-alanine-D-alanine ligase B; Cell wall formation. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.801 |
ddlB-2 | ftsQ | XCC0727 | XCC0728 | D-alanine-D-alanine ligase B; Cell wall formation. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.972 |
ddlB-2 | ftsW | XCC0727 | XCC0724 | D-alanine-D-alanine ligase B; Cell wall formation. | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.955 |
ddlB-2 | mraY | XCC0727 | XCC0723 | D-alanine-D-alanine ligase B; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.954 |
ddlB-2 | mrdA | XCC0727 | XCC3467 | D-alanine-D-alanine ligase B; Cell wall formation. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.468 |
ddlB-2 | murC | XCC0727 | XCC0726 | D-alanine-D-alanine ligase B; Cell wall formation. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.987 |
ddlB-2 | murE | XCC0727 | XCC0721 | D-alanine-D-alanine ligase B; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D- glutamate-2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.954 |
ddlB-2 | murF | XCC0727 | XCC0722 | D-alanine-D-alanine ligase B; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.997 |
ddlB-2 | murG | XCC0727 | XCC0725 | D-alanine-D-alanine ligase B; Cell wall formation. | UDP-N-acetylglucosamine-N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.974 |
ftsI | ddlB-2 | XCC0720 | XCC0727 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | D-alanine-D-alanine ligase B; Cell wall formation. | 0.942 |
ftsI | ftsL | XCC0720 | XCC0719 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.948 |
ftsI | ftsQ | XCC0720 | XCC0728 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.961 |
ftsI | ftsW | XCC0720 | XCC0724 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Cell division protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.992 |
ftsI | mraY | XCC0720 | XCC0723 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.955 |
ftsI | mrdA | XCC0720 | XCC3467 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.960 |
ftsI | murC | XCC0720 | XCC0726 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramate-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.976 |
ftsI | murE | XCC0720 | XCC0721 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D- glutamate-2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.990 |
ftsI | murF | XCC0720 | XCC0722 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.977 |
ftsI | murG | XCC0720 | XCC0725 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. | UDP-N-acetylglucosamine-N- acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.955 |