Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sahHAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (480 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.977
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.959
metH1
5-methyltetrahydrofolate-homocysteine methyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.943
cysB
Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.939
XCC2270
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
  0.920
metB-2
Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.917
metB-3
Homocysteine synthase PA5025 (imported); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.916
mmuM
Homocysteine S-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.914
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.890
cysM
Cysteine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.840
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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