STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (403 aa)    
Predicted Functional Partners:
speD
S-adenosyl methionine decarboxylase proenzyme; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.
    
 0.988
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 0.987
metH1
5-methyltetrahydrofolate-homocysteine methyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.973
mmuM
Homocysteine S-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.962
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.959
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
 
 
 0.944
metB-3
Homocysteine synthase PA5025 (imported); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 
 0.922
metF-2
5,10-methylenetetrahydrofolate reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the methylenetetrahydrofolate reductase family.
  
  
 0.920
tyrB
Aromatic-amino-acid aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.914
XCC0586
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
  0.900
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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