| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cysB | glyA | XCC0597 | XCC0690 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.949 |
| cysB | ilvA | XCC0597 | XCC0379 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Threonine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.930 |
| cysB | pgmA | XCC0597 | XCC0948 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the phosphoglycerate mutase family. | 0.908 |
| cysB | pssA | XCC0597 | XCC0641 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphatidylserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| cysB | pssA-2 | XCC0597 | XCC2161 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | CDP-diacylglycerol-serine o-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| cysB | sdaA | XCC0597 | XCC2853 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.918 |
| cysB | tdcB | XCC0597 | XCC3326 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Threonine dehydratase catabolic; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.930 |
| cysB | trpA | XCC0597 | XCC2541 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.923 |
| cysB | trpB | XCC0597 | XCC2543 | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.911 |
| glyA | cysB | XCC0690 | XCC0597 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.949 |
| glyA | ilvA | XCC0690 | XCC0379 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.915 |
| glyA | pgmA | XCC0690 | XCC0948 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoglycerate mutase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the phosphoglycerate mutase family. | 0.913 |
| glyA | pssA | XCC0690 | XCC0641 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphatidylserine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | pssA-2 | XCC0690 | XCC2161 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | CDP-diacylglycerol-serine o-phosphatidyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA | sdaA | XCC0690 | XCC2853 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-serine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.962 |
| glyA | serC | XCC0690 | XCC1589 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.639 |
| glyA | tdcB | XCC0690 | XCC3326 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase catabolic; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.915 |
| glyA | trpA | XCC0690 | XCC2541 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.934 |
| glyA | trpB | XCC0690 | XCC2543 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.926 |
| ilvA | cysB | XCC0379 | XCC0597 | Threonine dehydratase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Cystathionine beta-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.930 |