node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
XCC0958 | bacA | XCC0958 | XCC0184 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.913 |
XCC0958 | entF | XCC0958 | XCC3867 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | ATP-dependent serine activating enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.458 |
XCC0958 | gtrB-2 | XCC0958 | XCC0959 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Glycosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.888 |
XCC0958 | hflD | XCC0958 | XCC1963 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.442 |
XCC0958 | lpxH | XCC0958 | XCC0957 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.600 |
XCC0958 | mraY | XCC0958 | XCC0723 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.904 |
XCC0958 | oleC | XCC0958 | XCC0218 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | AMP-ligase; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl- 3-hydroxyalkanoic acids to beta-lactones in the presence of ATP ; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.419 |
XCC0958 | ppx | XCC0958 | XCC0960 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Exopolyphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the GppA/Ppx family. | 0.458 |
XCC0958 | rplF | XCC0958 | XCC0910 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.471 |
XCC0958 | uppS | XCC0958 | XCC1369 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.909 |
bacA | XCC0958 | XCC0184 | XCC0958 | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.913 |
bacA | mraY | XCC0184 | XCC0723 | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.928 |
bacA | uppS | XCC0184 | XCC1369 | Undecaprenol kinase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | Undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.926 |
entF | XCC0958 | XCC3867 | XCC0958 | ATP-dependent serine activating enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.458 |
entF | oleC | XCC3867 | XCC0218 | ATP-dependent serine activating enzyme; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | AMP-ligase; Involved in olefin biosynthesis. Catalyzes the conversion of 2-alkyl- 3-hydroxyalkanoic acids to beta-lactones in the presence of ATP ; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.990 |
gtrB-2 | XCC0958 | XCC0959 | XCC0958 | Glycosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.888 |
gtrB-2 | lpxH | XCC0959 | XCC0957 | Glycosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.524 |
gtrB-2 | ppx | XCC0959 | XCC0960 | Glycosyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Exopolyphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the GppA/Ppx family. | 0.461 |
hflD | XCC0958 | XCC1963 | XCC0958 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.442 |
lpxH | XCC0958 | XCC0957 | XCC0958 | Conserved hypothetical protein; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.600 |