STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
fabH-2beta-ketoacyl-[ACP] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)    
Predicted Functional Partners:
fabD
Malonyl CoA-ACP transacylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.998
fabF
3-oxoacyl-[ACP] synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 
 0.997
fabB
beta-ketoacyl-[ACP] synthase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.995
fabF-2
beta-ketoacyl-[ACP] synthase II; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 
 0.995
mdcH
Malonyl CoA-ACP transacylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.990
fabG-2
3-oxoacyl-[ACP] reductase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.973
fabZ
(3r)-hydroxymyristoyl ACP dehydrase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
  
 0.972
bccP
Biotin carboxyl carrier protein of acetyl-CoA; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.968
accC-2
Biotin carboxylase subunit of acetyl CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.964
fabG
3-oxoacyl-[ACP] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 0.964
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.