Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mmuMHomocysteine S-methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. (347 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 
 0.982
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.962
metB-2
Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.936
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.933
metH1
5-methyltetrahydrofolate-homocysteine methyl transferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
0.931
metL
Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family.
   
 
 0.923
tyrB
Aromatic-amino-acid aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
  
 0.922
ykfD
S-methylmethionine permease; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.917
sahH
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.914
metB-3
Homocysteine synthase PA5025 (imported); Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
     
 0.910
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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