STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (322 aa)    
Predicted Functional Partners:
metL
Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.999
thrC
Threonine synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 
 0.999
XCC2855
Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
 0.994
lysA
Bifunctional diaminopimelate decarboxylase/aspartate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
 
 
 0.953
met
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-serine, forming succinyl-L-serine. In vitro, has also homoserine succinyl transferase activity; Belongs to the AB hydrolase superfamily. MetX family.
     
 0.908
metA
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
     
 0.908
metB
Cystathionine gamma-lyase-like protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.848
metB-2
Cystathionine gamma-synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.848
metH2
5-methyltetrahydrofolate-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.839
ilvE
Branched-chain amino acid aminotransferase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
  
 
 0.837
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.