Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acnBAconitate hydratase 2; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the aconitase/IPM isomerase family. (863 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the citrate synthase family.
  
 
 0.972
rpfA
Aconitase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.967
prpC
Citrate synthase 2; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the citrate synthase family.
  
 
 0.964
icd-2
Isocitrate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the monomeric-type IDH family.
 
 
 0.963
odhA
Oxoglutarate dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
  
 0.939
aceA
Isocitrate lyase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
   
 
 0.935
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.928
prpB
Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
   
 
 0.922
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
  
 0.916
XCC1036
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
 0.908
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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