| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC2274 | XCC2275 | XCC2274 | XCC2275 | GGDEF family protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Phosphate-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.874 |
| XCC2274 | suhB | XCC2274 | XCC2277 | GGDEF family protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Extragenic supressor protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the inositol monophosphatase superfamily. | 0.487 |
| XCC2274 | trmJ | XCC2274 | XCC2276 | GGDEF family protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.715 |
| XCC2275 | XCC2274 | XCC2275 | XCC2274 | Phosphate-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | GGDEF family protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.874 |
| XCC2275 | suhB | XCC2275 | XCC2277 | Phosphate-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Extragenic supressor protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the inositol monophosphatase superfamily. | 0.490 |
| XCC2275 | trmJ | XCC2275 | XCC2276 | Phosphate-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.675 |
| cysS | dksA | XCC2251 | XCC2255 | cysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-I aminoacyl-tRNA synthetase family. | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.638 |
| cysS | rpoZ | XCC2251 | XCC3248 | cysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-I aminoacyl-tRNA synthetase family. | RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.405 |
| cysS | trmJ | XCC2251 | XCC2276 | cysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-I aminoacyl-tRNA synthetase family. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.521 |
| cysS | truB | XCC2251 | XCC2509 | cysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-I aminoacyl-tRNA synthetase family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.457 |
| dksA | cysS | XCC2255 | XCC2251 | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | cysteinyl-tRNA synthetase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.638 |
| dksA | ftsJ | XCC2255 | XCC1712 | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Cell division protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.596 |
| dksA | rpoZ | XCC2255 | XCC3248 | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.963 |
| dksA | trmJ | XCC2255 | XCC2276 | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.545 |
| dusA | ftsJ | XCC3945 | XCC1712 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | Cell division protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.425 |
| dusA | micA | XCC3945 | XCC3151 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | DNA mismatch repair protein; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.586 |
| dusA | trmJ | XCC3945 | XCC2276 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.629 |
| dusA | truB | XCC3945 | XCC2509 | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.627 |
| ftsJ | dksA | XCC1712 | XCC2255 | Cell division protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | DnaK supressor; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.596 |
| ftsJ | dusA | XCC1712 | XCC3945 | Cell division protein; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. | 0.425 |