Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fruK1-phosphofructokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the carbohydrate kinase PfkB family. (318 aa)    
Predicted Functional Partners:
fruB
Multiphosphoryl transfer protein; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
 
  
 0.999
fruA
PTS system,fructose-specificIIBC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport.
 
 
 0.999
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 0.934
cbbFC
Fructose-1,6-bisphosphatase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
    
 0.915
XCC3185
Fructose-bisphosphate aldolase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the class I fructose-bisphosphate aldolase family.
     
  0.900
ptsN
Nitrogen regulatory IIA protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.868
glpR
Glycerol-3-phosphate regulon repressor; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
  
 0.849
XCC2369
Transcriptional regulator lacI family; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
   
 0.803
scrK
Fructokinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark.
 
   
 0.771
ptsI
Phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
  
 0.722
Your Current Organism:
Xanthomonas campestris
NCBI taxonomy Id: 190485
Other names: X. campestris pv. campestris str. ATCC 33913, Xanthomonas campestris pv. campestris str. ATCC 33913
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