| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| XCC2739 | lysA | XCC2739 | XCC2741 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Bifunctional diaminopimelate decarboxylase/aspartate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.926 |
| XCC2739 | murD | XCC2739 | XCC2738 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine. Belongs to the MurCDEF family. MurD2 subfamily. | 0.998 |
| XCC2739 | murE | XCC2739 | XCC0721 | Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | UDP-N-acetylmuramoylalanyl-D- glutamate-2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.900 |
| XCC2855 | asd | XCC2855 | XCC2549 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.980 |
| XCC2855 | lysA | XCC2855 | XCC2741 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Bifunctional diaminopimelate decarboxylase/aspartate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.958 |
| XCC2855 | lysA-2 | XCC2855 | XCC3055 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.715 |
| XCC2855 | metL | XCC2855 | XCC1800 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.965 |
| XCC2855 | thrB | XCC2855 | XCC1801 | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.994 |
| argG | asd | XCC2247 | XCC2549 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.513 |
| argG | lysA | XCC2247 | XCC2741 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Bifunctional diaminopimelate decarboxylase/aspartate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.971 |
| argG | lysA-2 | XCC2247 | XCC3055 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.754 |
| argG | metL | XCC2247 | XCC1800 | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.931 |
| asd | XCC2855 | XCC2549 | XCC2855 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine dehydrogenase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.980 |
| asd | argG | XCC2549 | XCC2247 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Argininosuccinate synthase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.513 |
| asd | dapF | XCC2549 | XCC3499 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.509 |
| asd | lysA | XCC2549 | XCC2741 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Bifunctional diaminopimelate decarboxylase/aspartate kinase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; Belongs to the Orn/Lys/Arg decarboxylase class-II family. | 0.994 |
| asd | lysA-2 | XCC2549 | XCC3055 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark. | 0.848 |
| asd | metL | XCC2549 | XCC1800 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.998 |
| asd | thrB | XCC2549 | XCC1801 | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.775 |
| dapF | asd | XCC3499 | XCC2549 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.509 |